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Shiitake, scientific references

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Amagase H. et al.: L.E.M. May be Effective Against Treating Hepatitis B Cases. (1984). Abstr. 197 Gastroenterology World Congress, Lisbon

Arinaga S.: Enhanced induction of lymphokine-activated killer activity after lentinan administration in patients with gastric carcinoma. Int J Immunopharmacol. 1992;14(4): 535-53

Breene W. M: Nutritional & Medicinal Value of Exotic Mushrooms. Shiitake Mushrooms.The Proceeding of a National Symposium & Trade Show University of Minnesota. 1989:100-102

Brodziak L.: Nutritive value of the mushroom Lentinus edodes (Berk.) Sing. (shiitake) compared with that of other edible mushrooms Rocz Panstw Zakl Hig. 1984;35(1): 59-62

Chang, R: Functional properties of edible mushrooms; Nutr Rev. 1996;54 (11 Pt2):91-93

Cozens, D.D. et al. 1981a. The effect of lentinan on fertility and general reproductive performance of the rat. Toxicol. Lett. 9:55-64

Fruehauf JP.: The effect of lentinan on production of interleukin-1 by human monocytes. Immunopharmacology. 1982; 5(1), 65-7.

Hirasawa M, et al.: Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing. (Shiitake, an edible mushroom). Int J Antimicrob Agents. 1999;11(2):151-7.

Ishgami H., et al.: Relationship between prolonged life span and changes of serum IAP and albumin induced by the therapy of lentinan plus tagafur in inoperable and recurrent gastric cancer, Nippon geka Gakkai Zasshi. 1992;93:800-04

James, J. S. Shiitake, Lentinen, and AIDS/ARC. Aid Treatment News. 1986;19:1-6

Jong SC, Medicinal and therapeutic value of the shiitake mushroom. Adv Appl Microbiol (1993)39, 153-184

Jones K. Shiitake: A major medicinal mushroom. Alt Compl Ther 1998; 4:53-9 (review)

Kabir Y, Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987, 33(5), 341-346

Kanemoto, M. Acute Oral Toxicity Study of Lentinus edodes Mycelial Powder (Moncelium rtm powder) in Male and Female Mice, Biotechnical Research Laboratories, Inc., Tech. Report No. 830916A, (1983) Oct. 20.

Kupfahl C, Geginat G, Hof H. Lentinan has a stimulatory effect on innate and adaptive immunity against murine Listeria monocytogenes infection. Int Immunopharmacology 2006;6(4):686-96.

Kurashige S, Effects of Lentinus edodes, Grifola frondosa and Pleurotus ostreatus administration on cancer outbreak, and activities of macrophages and lymphocytes in mice treated with a carcinogen, N-butyl-N-butanolnitrosoamine. Immunopharmacol Immunotoxicol (1997) 19(2), 175-183

Levy, A.M., et al: Eosinophilia and gastrointestinal symptoms after ingestion of shiitake mushrooms, J Allergy Clin Immunol (1998), 101(5): pp613-20

Lin, Y. et al.: A double-blind treatment of 72 cases of chronic hepatitis with Lentinan injection. New Drugs and Clinical Remedies (1987) 6:362-363, from Abstracts of Chinese Medicines 2:325.

Maeda YY & G. Chihara. Lentinen, a new immuno-accelerator of cell mediated response. Nature (London) 1971, 229: 634

Matsuoka H.: Usefulness of lymphocyte subset change as an indicator for predicting survival time and effectiveness of treatment with the immunopotentiator lentinan. Anticancer Res (1995) 15(5B), 2291-2296

Matsuoka H.: Lentinan potentiates immunity and prolongs the survival time of some patients. Anticancer Res (1997) 17(4A), 2751-2755

Miyakoshi H.: Acting mechanisms of Lentinan in human-II. Enhancement of non-specific cell-mediated cytotoxicity as an interferon inducer. Int J Immunopharmacol (1984) 6(4), 373-379

Mizoguchi, Y. et al. Protection of liver cells against experimental damage by extract of cultured Lentinus edodes mycelia (LEM). Gast. Japonica (1987) 22:459-464

Mizoguchi, Y., et al. 1987. Determination of IL-1 Activity in the Supernatant of a Macrophage Culture Treated with LEM, Kantansui, vol. 15(1), pp. 127-135

Mizoguchi, Y. The Effects of LEM on the Induction of anti-TNP-SRBC Antibody Producing Cells by PWM Stimulation, Kantansui, 1987 vol. 15(1), pp. 127-135.

Mizono M, Preparation and specificity of antibodies to an anti-tumor beta-glucan, lentinan. Biochem Mol Biol Int 1996;39(4):679-85.

Nanba H, Kuroda H. Antitumor mechanisms of orally administered shiitake fruit bodies. Chem Pharm Bull (Tokyo) 1987;35(6):2459-64.

Taguchi T: Clinical efficacy of lentinan on patients with stomach cancer: End point results of a four-year follow-up Survey. Cancer detict Prevent Suppl 1987; 1:333-49

Takehara, M. et al. Antitumor effects of virus-like particles from Lentinus edodes (Shiitake) on Ehrlich Acsites Carcinoma in mice. Archiv Virology (1983) 68: 297-301.

Takeshita K, Effect of lentinan on lymphocyte subsets of peripheral blood, lymph nodes, and tumor tissues in patients with gastric cancer. Surg Today (1993) 23(2), 125-129

Takatsuki F, Lentinan augments skin reaction induced by bradykinin: its correlation with vascular dilatation and hemorrhage responses and antitumor activities. Int J Immunopharmacol (1995) 17(6), 465-474

Takeshita K, Monocyte function associated with intermittent lentinan therapy after resection of gastric cancer. Surg Oncol (1996) 5(1), 23-28

Tamura R, Effects of lentinan on abnormal ingestive behaviors induced by tumor necrosis factor. Physiol Behav (1997) 61(3), 399-410

Tan YH, High concentrations of mannitol in the shiitake mushroom Lentinula edodes. Microbios (1994) 78(318), 31-35 (1994)

Tani M, Augmentation of lymphokine-activated killer cell activity by lentinan. Anticancer Res (1993) 13(5C), 1773-1776

Tochikura S.T. et al. Suppression Human Immuno-Deficiency Virus Replication by 3-Azido -3- Deoxythymidine in Various Human Haematopoetic Cell Lines Invitro: Augmentation by the Effect of Lentinan. (1987) JPN. J. Cancer Res. (Gann) 78:583

Tochikura, T.S., et al. Inhibition (in vitro) of replication and of the cyptopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia, Med. Microbiol. Immunol., (1988) vol. 177, pp.235-244.

Vetter J, Mineral and amino acid contents of edible, cultivated shiitake mushrooms (Lentinus edodes) Z Lebensm Unters Forsch (1995) 201(1), 17-19

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