An advancing degenerative suffering in the weight-bearing joints. It is primarily the cartilage that is being worn down. A genetic predisposition and wrongly - and too little - use of the joints also play a role in the progression of osteoarthritis.
A disproportionately large accumulation of fat in the body's connective tissues. A condition where the body over a period of time has received more calories than it has been able to burn and therefore has deposited this surplus energy as fat.